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Antigenic Specificity | MINA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the amino terminus of human MINA. |
Other Names | [Myc induced nuclear antigen, MINA53, MDIG, NO52] |
Gene, Accession # | [MINA], Gene ID: 84864, NCBI: NP_694822 |
Catalog # | MBS9411968 |
Price | $320 |
Order / More Info | MINA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |