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Antigenic Specificity | GPS2 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against GPS2. It was validated on Western BlotTarget Description: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPS2 |
Other Names | [G protein pathway suppressor 2; G protein pathway suppressor 2; G protein pathway suppressor 2] |
Gene, Accession # | [GPS2], Gene ID: 2874, NCBI: XP_005256674, UniProt: Q13227 |
Catalog # | MBS3219222 |
Price | $335 |
Order / More Info | GPS2 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |