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Antigenic Specificity | Human GTP-binding nuclear protein Ran |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases. |
Immunogen | Immunogen: Recombinant human GTP-binding nuclear protein Ran protein (1-216aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1156 / sc-1155 / sc-20802 |
Other Names | [Androgen receptor-associated protein 24; GTPase Ran; Ras-like protein TC4; Ras-related nuclear protein; RAN; ARA24], [RAN; RAN; TC4; Gsp1; ARA24; ARA24] |
Gene, Accession # | [RAN], Gene ID: 5901, NCBI: NP_001287725.1, UniProt: P62826 |
Catalog # | MBS1497286 |
Price | $120, $160 |
Order / More Info | Human GTP-binding nuclear protein Ran Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |