CCDC8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CCDC8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CCDC8 antibody detects endogenous levels of total CCDC8. Function: Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695).Subunit Structure: Component of the 3M complex, composed of core components CUL7, CCDC8 and OBSL1 (PubMed:21737058, PubMed:24793695). Interacts (via PxLPxI/L motif) with ANKRA2 (via ankyrin repeats); may link the 3M complex to histone deacetylases including HDAC4 and HDAC5 (PubMed:25752541).Similarity: The PxLPxI/L motif me |
| Immunogen | Immunogen: A synthesized peptide derived from human CCDC8 Subcellular Location: Cytoskeleton Tissue Specificity: Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep Similarity: Pig (100%), Bovine (83%), Horse (100%), Sheep (83%) |
| Other Names | [CCDC8; CCDC8_HUMAN; Coiled-coil domain-containing protein 8; DKFZp564K0322; ENSMUSG00000041117; MGC72567] |
| Gene, Accession # | [CCDC8], Gene ID: 83987, NCBI: NP_114429.2, UniProt: Q9H0W5 |
| Catalog # | MBS9609722 |
| Price | $240, $280 |
| Order / More Info | CCDC8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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