NRBP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNRBP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: NRBP1 antibody detects endogenous levels of total NRBP1. Function: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.Subunit Structure: Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm (By similarity).Similarity: The protein kinase domain is predicted to be catalytically inactive. Belongs to the protein kinase superfamily. Ser/Thr prot
ImmunogenImmunogen: A synthesized peptide derived from human NRBP1 Subcellular Location: Cytoplasm > Cell Cortex. Endomembrane System. Cell Projection > Lamellipodium. Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia. Tissue Specificity: Ubiquitously expressed in all tissues examined with high levels in the testis. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100
Other Names[BCON3; MADM; MUDPNP; Multiple domain putative nuclear protein; Myeloid leukemia factor 1 adaptor molecule; NRBP; NRBP_HUMAN; NRBP1; Nuclear receptor binding protein; Nuclear receptor-binding protein]
Gene, Accession #[NRBP1], Gene ID: 29959, NCBI: NP_001308286.1, UniProt: Q9UHY1
Catalog #MBS9603005
Price$240, $280
Order / More InfoNRBP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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