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Antigenic Specificity | NRBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NRBP1 antibody detects endogenous levels of total NRBP1. Function: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.Subunit Structure: Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm (By similarity).Similarity: The protein kinase domain is predicted to be catalytically inactive. Belongs to the protein kinase superfamily. Ser/Thr prot |
Immunogen | Immunogen: A synthesized peptide derived from human NRBP1 Subcellular Location: Cytoplasm > Cell Cortex. Endomembrane System. Cell Projection > Lamellipodium. Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia. Tissue Specificity: Ubiquitously expressed in all tissues examined with high levels in the testis. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100 |
Other Names | [BCON3; MADM; MUDPNP; Multiple domain putative nuclear protein; Myeloid leukemia factor 1 adaptor molecule; NRBP; NRBP_HUMAN; NRBP1; Nuclear receptor binding protein; Nuclear receptor-binding protein] |
Gene, Accession # | [NRBP1], Gene ID: 29959, NCBI: NP_001308286.1, UniProt: Q9UHY1 |
Catalog # | MBS9603005 |
Price | $240, $280 |
Order / More Info | NRBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |