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Antigenic Specificity | ERK1/2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have alr |
Immunogen | Immunogen: A synthesized peptide derived from human ERK1/2. Subcellular Localization: Cytoplasm. Nucleus. Autophosphorylation at Thr-207 promotes nuclear localization. |
Other Names | [Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1; MAPK3; ERK1; PRKM3], [MAPK3; MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; ERK1; PRKM3; MAP kinase 3; MAPK 3; ERK-1; p44-MAPK] |
Gene, Accession # | [MAPK3], Gene ID: 5595, NCBI: NP_001035145.1, UniProt: P27361 |
Catalog # | MBS179108 |
Price | $160, $340, $340 |
Order / More Info | ERK1/2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |