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Antigenic Specificity | SIN3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Sin3B Polyclonal Antibody detects endogenous levels of Sin3B protein. SIN3B (SIN3 Transcription Regulator Family Member B) is a Protein Coding gene. Paired amphipathic helix protein Sin3b acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. Among its related pathways are Gene Expression and Metabolism. Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase II transcription corepressor activity. An important paralog of this g |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Sin3B at AA range: 190-270 |
Other Names | [Rabbit Sin3B; SIN3B; KIAA0700; Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b] |
Gene, Accession # | [SIN3B], Gene ID: 23309, NCBI: NP_056075.1, UniProt: O75182 |
Catalog # | MBS9702551 |
Price | $130, $220, $325 |
Order / More Info | SIN3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |