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Antigenic Specificity | XAF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | XAF1 binds to XIAP, an inhibitor of caspases-3, -7, -9 and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines. |
Immunogen | Immunogen: XAF1 antibody was raised in Rabbit using synthetic peptide surrounding aa 306 of human XAF-1 as the immunogen. |
Other Names | [Rabbit XAF1; XAF1; XAF1; XAF 1; XIAP; XAF-1; BIRC 4; XAF1; HSXIAPAF1; XAF-1; XAF-1; BIRC4; XAF 1; XAF 1; HSXIAPAF 1] |
Gene, Accession # | [XAF1] |
Catalog # | MBS5311430 |
Price | $430 |
Order / More Info | XAF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |