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Antigenic Specificity | NT5E |
Clone | [1D7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: 5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73). Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 |
Immunogen | Immunogen: Purified recombinant fragment of NT5E expressed in E Coli. |
Other Names | [eN; NT5; CD73], [eN; NT5; CD73] |
Gene, Accession # | [NT5E], Gene ID: 4907, NCBI: AAH15940.1 |
Catalog # | MBS475938 |
Price | $335 |
Order / More Info | NT5E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |