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Antigenic Specificity | Integrin alpha 5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Integrin alpha 5 Antibody detects endogenous levels of total Integrin alpha 5. Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. |
Immunogen | Immunogen: A synthesized peptide derived from human Integrin alpha 5 |
Other Names | [Integrin alpha-5; VLA-5; CD49e; FNRA] |
Gene, Accession # | [ITGA5], Gene ID: 3678, NCBI: NP_002196.4, UniProt: P08648 |
Catalog # | MBS4750281 |
Price | $335 |
Order / More Info | Integrin alpha 5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |