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Antigenic Specificity | Human Transthyretin |
Clone | [PAT7B2AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Transthyretin (TTR) is a circulating and abundant tetramer, which functions as a carrier protein of thyroid hormone and retinol binding protein. It is primarily produced in the liver, but also in the brain and eye. Mutations in the TTR gene cause the protein to dissociate into monomers that after misfolding assemble into amyloid fibrils deposits in a variety of organs. TTR is also the only gene known to be associated with familial TTR amyloidosis. The diseases that originate from mutations in the TTR gene include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. |
Immunogen | Immunogen: Anti-human TTR mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TTR amino acids 21-147 purified from E Coli. |
Other Names | [TTR; Transthyretin, Mouse Human; Transthyretin; ATTR; Prealbumin; TBPA; TTR; PALB; HsT2651], [TTR; TTR; CTS; CTS1; PALB; TBPA; HEL111; HsT2651; PALB] |
Gene, Accession # | [TTR], Gene ID: 7276, NCBI: NP_000362.1 |
Catalog # | MBS140342 |
Price | $140, $205, $505 |
Order / More Info | Human Transthyretin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |