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Antigenic Specificity | NRAS |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. |
Immunogen | Immunogen: A synthetic peptide of human NRAS |
Other Names | [ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6] |
Gene, Accession # | [NRAS], Gene ID: 4893, NCBI: P01111.1, UniProt: P01111 |
Catalog # | MBS9131826 |
Price | $275, $430 |
Order / More Info | NRAS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |