Copper Transporting ATPase 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Copper Transporting ATPase 2 |
| Clone | [S62-29] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~160 kDa in rat brain membrane preparations. The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage. |
| Immunogen | Immunogen: Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2 |
| Other Names | [Mouse Human Copper Transporting ATPase 2 IgG1; Copper Transporting ATPase 2 : APC/Cy7; ATP7B; ATPase Cu++ transporting beta polypeptide; ATPase Cu(2+) transporting beta polypeptide; Copper pump 2; Copper transporting ATPase 2; PWD; Toxic milk; tx; WC1; WD; Wilson disease associated protein; WND; WND/140 kDa] |
| Gene, Accession # | [ATP7B], Gene ID: 540, NCBI: NP_000044.2, UniProt: B7ZLR4 |
| Catalog # | MBS8003088 |
| Price | $510 |
| Order / More Info | Copper Transporting ATPase 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Tanzi R.E., et al. (1993) Nature Genetics. 5: 344-350. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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