Edit |   |
---|---|
Antigenic Specificity | SULF1 (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | 1.45 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SULF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 704-738 amino acids from human SULF1. Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation. |
Immunogen | n/a |
Other Names | [Extracellular sulfatase Sulf-1; hSulf-1; 3.1.6.-; SULF1; KIAA1077; Purified Rabbit (Pab)] |
Gene, Accession # | [SULF1], Gene ID: 23213, NCBI: Q8IWU6.1, UniProt: Q8IWU6 |
Catalog # | MBS9217328 |
Price | $165, $370 |
Order / More Info | SULF1 (C-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Morimoto-Tomita M.,et al.J. Biol. Chem. 277:49175-49185(2002). Lai J.,et al.J. Biol. Chem. 278:23107-23117(2003). Kikuno R.,et al.DNA Res. 6:197-205(1999). Ota T.,et al.Nat. Genet. 36:40-45(2004). Chen R.,et al.J. Proteome Res. 8:651-661(2009). |