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Antigenic Specificity | Phospho-Mouse BAD (T94) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T94 of mouse BAD. Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. |
Immunogen | n/a |
Other Names | [Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; Bad; Bbc6] |
Gene, Accession # | [Bad], Gene ID: 12015, NCBI: NP_031548.1, UniProt: Q61337 |
Catalog # | MBS9207691 |
Price | $165, $370 |
Order / More Info | Phospho-Mouse BAD (T94) Antibody from MYBIOSOURCE INC. |
Product Specific References | Santidrian, A.F., et al. Blood 116(16):3023-3032(2010) Frenzel, A., et al. Blood 115(5):995-1005(2010) Quoyer, J., et al. J. Biol. Chem. 285(3):1989-2002(2010) Polzien, L., et al. J. Biol. Chem. 284(41):28004-28020(2009) Wu, X., et al. Diabetologia 52(10):2130-2141(2009) |