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Antigenic Specificity | Human Transient receptor potential cation channel subfamily V member 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca2+ in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation |
Immunogen | Immunogen: Recombinant human Transient receptor potential cation channel subfamily V member 4 protein (1-230aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-16485 / sc-47527 / sc-98592 |
Other Names | [TrpV4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC; TRPV4; VRL2; VROAC], [TRPV4; TRPV4; SMAL; VRL2; BCYM3; CMT2C; SPSMA; TRP12; VROAC; HMSN2C; OTRPC4; SSQTL1; VRL2; VROAC; TrpV4; OTRPC4; TRP12; VRL-2; VR-OAC] |
Gene, Accession # | [TRPV4], Gene ID: 59341, NCBI: NP_001170899.1, UniProt: Q9HBA0 |
Catalog # | MBS1491899 |
Price | $120, $160 |
Order / More Info | Human Transient receptor potential cation channel subfamily V member 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |