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Antigenic Specificity | CAF1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CAF1B antibody detects endogenous levels of total CAF1B. Function: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.Subunit Structure: Subunit of the CAF-1 complex that contains RBBP4, CHAF1B and CHAF1A. CHAF1A binds directly to CHAF1B. Only minor amounts of RBBP4 are complexed with CHAF1A and CHAF1B in G1 phase. In G2 and S phase also monomeric CHAF1B is detected.Post-translation |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Cytoplasm. DNA replication foci. Cytoplasmic in M phase. Tissue Specificity: Active complex is found in G1, S and G2 phases. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Zebrafish (90%), Bovine (91%), Horse (100%), Sheep (91%), Rabbit (100%), Dog (91%) |
Other Names | [CAF 1 subunit B; CAF 1A; CAF I 60 kDa subunit; CAF IP60; CAF-1; CAF-1 subunit B; CAF-I 60 kDa subunit; CAF-I p60; CAF1; CAF1A; CAF1B_HUMAN; CAF1P60; CHAF 1B; CHAF1B; Chromatin assembly factor 1 subunit B; Chromatin assembly factor I; Chromatin assembly factor I p60 subunit; Human chromatin assembly factor-I p60 subunit; M phase phosphoprotein 7; M-phase phosphoprotein 7; MPHOSPH7; MPP 7; MPP7; p60 subunit] |
Gene, Accession # | [CAF1B], Gene ID: 8208, NCBI: NP_005432.1, UniProt: Q13112 |
Catalog # | MBS9604717 |
Price | $240, $280 |
Order / More Info | CAF1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |