Mouse IL-6 receptor Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse IL-6 receptor
Clone[14F33]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2
FormatProtein A purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) - Formalin
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DescriptionThis antibody detects mouse IL-6R in Western blotting. The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6 R) and a signal-transducing component of 130 kDa (gp 130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. A soluble form of the IL-6 R alpha has been found in the urine of healthy adult humans. This soluble receptor apparently arises from proteolytic cleavage of membrane-bound IL-6 R alpha. No naturally-occurring mRNA encoding a truncated form of the IL-6 R alpha has been reported. Soluble forms of human a
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-6R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Other Names[mouse Interleukin-6 Receptor (#14F33)], [Il6ra; Il6ra; Il6r; CD126; IL-6R; Il6r; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA]
Gene, Accession #[IL-6 receptor], Gene ID: 16194, NCBI: NP_034689.2, UniProt: P22272
Catalog #MBS690088
Price$490
Order / More InfoMouse IL-6 receptor Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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