Edit |   |
---|---|
Antigenic Specificity | PKM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Pyruvate kinase isozymes M1/M2(PKM) detection. Tested with WB in Human, Mouse, Rat. Background: PKM(Pyruvate Kinase, Muscle), also known as PK3 or PKM2, is an enzyme that in humans is encoded by the PKM gene. The activity of pyruvate kinase subtype M2 is increased by fructose 1, 6-bisphosphate(Fru-1, 6-P2). By in situ hybridization, Popescu and Cheng(1990) mapped the THBP1 gene to 15q24-q25.Ashizawa et al.(1991) manipulated the intracellular Fru-1, 6-P2 concentration in several mammalian cell lines, including human, by varying the glucose concentration in the media. Using a novel proteomic screen for phosphotyrosine-binding proteins, Christofk et al.(2008) observed that PKM2 binds directly and |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PKM2 (77-91aa SHGTHEYHAETIKNV), identical to the related rat and mouse sequences. |
Other Names | [Pyruvate kinase isozymes M1/M2; pyruvate kinase, muscle; CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM_HUMAN; MGC3932; OIP 3; OIP-3; Oip3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK Muscle type; PK, muscle type; PK2; Pk3; PKM; PKM2; PYKM; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; Pyruvate kinase, muscle 2; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone-binding protein 1; Tumor M2 PK; Tumor M2-PK], [PKM; PKM; PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; OIP3; PK2; PK3; PKM2; CTHBP; OIP-3; THBP1] |
Gene, Accession # | [PKM], Gene ID: 5315, NCBI: P14618.4, UniProt: P14618 |
Catalog # | MBS176145 |
Price | $280 |
Order / More Info | PKM2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |