Human JNK2/MAPK9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman JNK2/MAPK9
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.06 mL, 0.12 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionMitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, such as c-Jun and ATF2. The crystal structure of human JNK2 complexed with an indazole inhibitor by applying a high-throughput protein engineering and surface-site mutagenesis approach. A novel conformation of the activation loop is observed, which is not compatible with its phosphorylation by upstream kinases. This activation inhibitory conformation of JNK2 is stabilized by the MAP kinase insert that interacts with the activation l
ImmunogenImmunogen: Recombinant Human JNK2/MAPK9 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose
Other Namesn/a
Gene, Accession #[JNK2/MAPK9 ]
Catalog #MBS2544062
Price$215, $330, $500
Order / More InfoHuman JNK2/MAPK9 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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