NEFL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNEFL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.6 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total NEFL protein. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human neurofilament, light polypeptide
Other Names[NFL; NF-L; NF68; CMT1F; CMT2E]
Gene, Accession #[NEFL], Gene ID: 4747, NCBI: NP_006149.2, UniProt: P07196
Catalog #MBS9414828
Price$255
Order / More InfoNEFL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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