Edit |   |
---|---|
Antigenic Specificity | NEFL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.6 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NEFL protein. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human neurofilament, light polypeptide |
Other Names | [NFL; NF-L; NF68; CMT1F; CMT2E] |
Gene, Accession # | [NEFL], Gene ID: 4747, NCBI: NP_006149.2, UniProt: P07196 |
Catalog # | MBS9414828 |
Price | $255 |
Order / More Info | NEFL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |