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Antigenic Specificity | RAB31 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human RAB31 (NP 006859.2). |
Other Names | [Rab22B] |
Gene, Accession # | [RAB31], Gene ID: 11031, NCBI: NP_006859.2, UniProt: Q13636 |
Catalog # | MBS8545262 |
Price | $280 |
Order / More Info | RAB31 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |