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Antigenic Specificity | HP1BP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HP1BP3 Antibody detects endogenous levels of HP1BP3. Description: Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal(PubMed:25100860).Subunit Structure: Interacts (via PxVxL motif) with CBX5 (via Trp-174).Similarity: A central region that included the first H15 (linker histone H1/H5 globular) domain binds at the entry/exit site of the nucleosomal DNA. |
Immunogen | Immunogen: A synthesized peptide derived from human HP1BP3. |
Other Names | [Heterochromatin protein 1, binding protein 3; Heterochromatin protein 1-binding protein 3; HP1 BP74; HP1B3_HUMAN; HP1BP 3; HP1BP3; MGC28927; MGC43701; MGC72624; OTTHUMP00000002717; OTTHUMP00000002719; OTTHUMP00000002720; Protein HP1 BP74; Protein HP1-BP74; RP5 930J4.3] |
Gene, Accession # | [HP1BP3], Gene ID: 50809, NCBI: AAH45660.1, UniProt: Q5SSJ5 |
Catalog # | MBS9611821 |
Price | $240, $280 |
Order / More Info | HP1BP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |