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Antigenic Specificity | PACS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PACS1 protein. PACS1 (Phosphofurin Acidic Cluster Sorting Protein 1) encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PACS1 protein at amino acid sequence of 400-480 |
Other Names | [Rabbit PACS1; Phosphofurin acidic cluster sorting protein 1; PACS-1] |
Gene, Accession # | [PACS1], Gene ID: 55690, NCBI: NP_060496, UniProt: Q6VY07 |
Catalog # | MBS9710362 |
Price | $130, $220, $325 |
Order / More Info | PACS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |