Edit |   |
---|---|
Antigenic Specificity | CHRNA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CHRNA3 protein. This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Synthetic peptide corresponding to a region derived from 69-83 amino acids of Human cholinergic receptor, nicotinic, alpha 3 (neuronal) |
Other Names | [cholinergic receptor, nicotinic, alpha 3 (neuronal), LNCR2, PAOD2, NACHRA3] |
Gene, Accession # | [CHRNA3], Gene ID: 1136, NCBI: NP_000734 |
Catalog # | MBS9403709 |
Price | $200, $255 |
Order / More Info | CHRNA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |