Edit |   |
---|---|
Antigenic Specificity | IL-1RL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA, IF, IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist; this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1. IL-1RL2 is a member of the interleukin 1 receptor family, but it is incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity (1). Together with IL-1RAcP, it can bind members of the IL-36 cytokine family, leading to activation of the NF-kappaB pathway (2). IL-1RL2 can also bind to IL-1F10, resulting in a decreased product of Th17 cytokines in response to immunological or LPS challenge, suggesting that one potential role of IL-1RL2 may be to modulate the immune and inflammation res |
Immunogen | Immunogen: IL-1RL2 antibody was raised against a 16 amino acid peptide near the center of human IL-1RL2. The immunogen is located within amino acids 260-310 of IL-1RL2. Buffer: IL-1RL2 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-1RL2; IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2; Interleukin-1 receptor-like 2; IL-36 receptor; IL-36R;], [IL1RL2; IL1RL2; IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2; IL1RRP2; IL-36R; IL-1Rrp2; IL1R-rp2] |
Gene, Accession # | [IL1RL2], Gene ID: 8808, NCBI: NP_003845, UniProt: Q9HB29 |
Catalog # | MBS153514 |
Price | $375 |
Order / More Info | IL-1RL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |