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Antigenic Specificity | ADAMTS4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, i |
Immunogen | Immunogen: ADAMTS4 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human ADAMTS4, different from the related rat and Rabbit sequences by three amino acids, as the immunogen |
Other Names | [Affinity Purified Rabbit ADAMTS4; ADAMTS4; ADAMTS4; Adam Metallopeptidase With Thrombospondin Type 1 Motif 4; ADAMTS-4; KIAA0688; ADMP-1; ADAMTS-2] |
Gene, Accession # | [ADAMTS4], Gene ID: 9507, UniProt: O75173 |
Catalog # | MBS5312791 |
Price | $345 |
Order / More Info | ADAMTS4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |