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Antigenic Specificity | SENP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SENP2 antibody detects endogenous levels of total SENP2. Function: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and prom |
Immunogen | Immunogen: A synthesized peptide derived from human SENP2 Subcellular Location: Nucleus > Nuclear Pore Complex. Nucleus Membrane. Cytoplasm. Shuttles between cytoplasm and nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (92%), Bovine (92%), Horse (92%), Sheep (92%), Dog (92%) |
Other Names | [Axam2; DKFZp762A2316; KIAA1331; Senp2; SENP2_HUMAN; Sentrin specific protease 2; Sentrin-specific protease 2; Sentrin/SUMO specific protease SENP2; Sentrin/SUMO-specific protease SENP2; SMT3 specific isopeptidase 2; SMT3-specific isopeptidase 2; Smt3ip2; SUMO1/sentrin/SMT3 specific peptidase 2] |
Gene, Accession # | [SENP2], Gene ID: 59343, NCBI: NP_067640.2, UniProt: Q9HC62 |
Catalog # | MBS9608747 |
Price | $240, $280 |
Order / More Info | SENP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |