b-Amyloid 1-40, 42, CT Antibody from MYBIOSOURCE INC.

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Antigenic Specificityb-Amyloid 1-40, 42, CT
Clone[6D4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatpurified
Size0.1 mg
Concentration0.1mg/ml
ApplicationsELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC). Other applications have not been tested.
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DescriptionRecognizes human C-terminal b-amyloid (aa1-40 and aa1-42). Crossreactivity: APP. The beta-amyloid peptide (beta A4), proteolytically released from the amyloid precursor protein (APP), is the principal component of senile plaques in Alzheimer's disease. Cleavage of APP by alpha-secretase or alternatively by beta-secretase leads to generation and extracellular release of soluble APP peptides, S-APP-alpha and S-APP-beta, respectively, and the retentionof corresponding membrane-anchored C-terminal fragments, C83 and C99. Subsequent processing of C83 by gamma-secretase yields P# peptides. This is the major secretory pathway and is nonamyloidogenic. Alternatively, presenilin/ nicastrin-mediated gamma-secretase processing of C99 releases the amylo
ImmunogenImmunogen: Synthetic peptide corresponding to aa1-40 and aa1-42 of C-terminal human b-amyloid, conjugated to KLH.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS603141
Price$730
Order / More Infob-Amyloid 1-40, 42, CT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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