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Antigenic Specificity | TBCC (N-term), 20-49 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.36 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human TBCC. Cofactor C is one of four proteins (cofactors A, D, E, andC) involved in the pathway leading to correctly folded beta-tubulinfrom folding intermediates. Cofactors A and D are believed to playa role in capturing and stabilizing beta-tubulin intermediates in aquasi-native confirmation. Cofactor E binds to the cofactorD/beta-tubulin complex; interaction with cofactor C then causes therelease of beta-tubulin polypeptides that are committed to thenative state. |
Immunogen | n/a |
Other Names | [Tubulin-specific chaperone C; Tubulin-folding cofactor C; CFC; TBCC] |
Gene, Accession # | [TBCC], Gene ID: 6903, NCBI: NP_003183.1, UniProt: Q15814 |
Catalog # | MBS9202609 |
Price | $165, $370 |
Order / More Info | TBCC (N-term), 20-49 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hage-Sleiman, R., et al. BMC Cancer 10, 135 (2010) : Nature 447(7145):661-678(2007) Mungall, A.J., et al. Nature 425(6960):805-811(2003) Bartolini, F., et al. J. Biol. Chem. 277(17):14629-14634(2002) Tian, G., et al. Cell 86(2):287-296(1996) |