Phospho-EPS15(Tyr849) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-EPS15(Tyr849) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-EPS15(Tyr849) antibody detects endogenous levels of EPS15 only when phosphorylated at Tyrosine 849. Description: This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.Function: Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) |
| Immunogen | Immunogen: A synthesized peptide derived from human EPS15 around the phosphorylation site of Tyrosine 849 Subcellular Location: Cytoplasm. Cell Membrane; Peripheral Membrane Protein; Cytoplasmic Side. Recruited to the plasma membrane upon EGFR activation and localizes to coated pits. Tissue Specificity: Ubiquitously expressed. |
| Other Names | [AF 1P; AF 1p protein; AF1P; ALL1 fused gene from chromosome 1; Epidermal growth factor receptor pathway substrate 15; Epidermal growth factor receptor substrate 15; EPS 15; MLLT 5; MLLT5; Protein Eps 15; Protein Eps15] |
| Gene, Accession # | [EPS15], Gene ID: 2060, NCBI: NP_001153441.1, UniProt: P42566 |
| Catalog # | MBS9600026 |
| Price | $240, $280 |
| Order / More Info | Phospho-EPS15(Tyr849) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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