Human CD272(BTLA) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD272(BTLA) antibody, protein, ELISA kits.
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| Antigenic Specificity | Human CD272(BTLA) |
| Clone | [ANC6E9] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1k |
| Format | purified |
| Size | 0.1 mg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the Immunoglobulin superfamily and has sequence homology to PD-1 and CTLA4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand, CD270(HVEM, a TNF superfamily member) can down regulate activated T and B cell responses. CD272 levels on antigen specific CD8 T cells have been reported to decrease in viral specific, but not melanoma specific activated lines (1). Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis (3). Antibody from clone ANC5A5 binds to CD272 on the cell surface of human PBMC in Flow cytometry and to recombinant CD272-muIg in EIA. This antibody does not block binding of |
| Immunogen | Immunogen: Recombinant extracellular human CD272 |
| Other Names | n/a |
| Gene, Accession # | [CD272] |
| Catalog # | MBS666053 |
| Price | $310 |
| Order / More Info | Human CD272(BTLA) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Derre' L, DE Speiser, et al. (2010) J Clin Invest 120(1):157-167. 2) Otsuki N, Azuma M, et al. (2006) Biochem Biophys Res Com 344(4): 1121-1127. 3) Lin SC, Chan CH, et al. (2006) J Biomed Sci 13(6): 853-860. 4) Pasero C, D Olive, et al. (2009) Curr Mol Med 9(7): 911-927. 5) Gavrieli M, KM Murphy, et al. (2006) Adv Immunol 92: 152-185. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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