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Antigenic Specificity | TNFR-S274, 252-281 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TNFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from human TNFR. The protein encoded by this gene is a member of theTNF-receptor superfamily. This protein is one of the majorreceptors for the tumor necrosis factor-alpha. This receptor canactivate NF-kappaB, mediate apoptosis, and function as a regulatorof inflammation. Antiapoptotic protein BCL2-associated athanogene 4(BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown tointeract with this receptor, and thus play regulatory roles in thesignal transduction mediated by the receptor. Germline mutations ofthe extracellular domains of this receptor were found to beassociate |
Immunogen | n/a |
Other Names | [Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD120a; Tumor necrosis factor receptor superfamily member 1A; membrane form; Tumor necrosis factor-binding protein 1; TBPI; TNFRSF1A; TNFAR; TNFR1] |
Gene, Accession # | [TNFRSF1A], Gene ID: 7132, NCBI: NP_001056.1, UniProt: P19438 |
Catalog # | MBS9208994 |
Price | $165, $370 |
Order / More Info | TNFR-S274, 252-281 Antibody from MYBIOSOURCE INC. |
Product Specific References | Giroux, S., et al. Bone 47(5):975-981(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Wolanska, M., et al. Ginekol. Pol. 81(6):431-434(2010) Sainz, J., et al. Int J Immunopathol Pharmacol 23(2):423-436(2010) |