FLNB Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFLNB
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionFilamins are a family of dimeric actin binding proteins that function as structural components of cell adhesion sites. They also serve as a scaffold for subcellular targeting of signaling molecules (1). The actin binding domain (alpha-actinin domain) located at the amino terminus is followed by as many as 24 tandem repeats of about 96 residues and the dimerization domain is located at the carboxy terminus. In addition to actin filaments, filamins associate with other structural and signaling molecules such as beta integrins, Rho/Rac/Cdc42, PKC, and the insulin receptor, primarily through the carboxy-terminal dimerization domain (1-3). Filamin A, the most abundant, and filamin B are widely expressed isoforms, while filamin C is predominantly
ImmunogenImmunogen: A synthetic peptide of human FLNB Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[ABP-278; AOI; DKFZp686A1668; DKFZp686O033; FH1; FLN1L; LRS1; SCT; TABP; TAP]
Gene, Accession #[FLNB], Gene ID: 2317, NCBI: NP_001157789.1, UniProt: O75369
Catalog #MBS8503495
Price$310
Order / More InfoFLNB Antibody from MYBIOSOURCE INC.
Product Specific References1. Stossel, T. P. et al. (2001) Nat. Rev. Mol. Cell Biol. 2, 138-145. 2. Tigges, U. et al. (2003) J. Biol. Chem. 278, 23561-23569. 3. He, H. et al. (2003) J. Biol. Chem. 278, 27096-27104. 4. Vadlamudi, R. K. et al. (2002) Nat. Cell Biol. 4, 681-690.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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