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Antigenic Specificity | ADAM10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Proinflammatory cytokine tumor necrosis factoralpha contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM, was recently identified to cleave TNF-alpha, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM10, kuzbanian, and MADM, respectively. ADAM10 mRNA is expre |
Immunogen | Immunogen: ADAM10 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human ADAM10 (612-627aa, SVQWSRHFSGRTITLQ) as the immunogen |
Other Names | [Affinity Purified Rabbit ADAM10; ADAM10; ADAM10; HsT18717; CD156c; ADAM10; kuz; ADAM 10; ADAM-10; CDw156; ADAM-10; EC 3.4.24.81; MADM; ADAM 10] |
Gene, Accession # | [ADAM10], Gene ID: 102 |
Catalog # | MBS5312843 |
Price | $345 |
Order / More Info | ADAM10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |