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Antigenic Specificity | ERCC1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. |
Immunogen | Immunogen: A synthesized peptide derived from human ERCC1. Subcellular Localization: Isoform 1: Nucleus. |
Other Names | [DNA excision repair protein ERCC-1; ERCC1], [ERCC1; ERCC1; UV20; COFS4; RAD10] |
Gene, Accession # | [ERCC1], Gene ID: 2067, NCBI: NP_001159521.1, UniProt: P07992 |
Catalog # | MBS179301 |
Price | $160, $340, $340 |
Order / More Info | ERCC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |