Cortactin/CTTN Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cortactin/CTTN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Direct ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Cortactin detection. Tested with WB, IHC-P, IHC-F, ICC, FCM, IF, Direct ELISA in Human; Mouse; Rat.Background: Cortactin, mapped to 11q13.3, is a multidomain protein. This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The |
| Immunogen | Immunogen: E Coli-derived human Cortactin recombinant protein (Position: M1-Q105). |
| Other Names | [Src substrate cortactin; Amplaxin; Oncogene EMS1; CTTN; EMS1; Cortactin] |
| Gene, Accession # | [CTTN], Gene ID: 2017, NCBI: NP_001171669.1, UniProt: Q14247 |
| Catalog # | MBS1751321 |
| Price | $315 |
| Order / More Info | Cortactin/CTTN Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Tegtmeyer, N., Wittelsberger, R., Hartig, R., Wessler, S., Martinez-Quiles, N., Backert, S. Serine phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori. Cell Host Microbe 9: 520-531, 2011. 2. Williams, M. R., Markey, J. C., Doczi, M. A., Morielli, A. D. An essential role for cortactin in the modulation of the potassium channel Kv1.2. Proc. Nat. Acad. Sci. 104: 17412-17417, 2007. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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