Apaf1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Apaf1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 100ug/100ul |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | Immunogen: Rabbit polyclonal APAF1 (1) antibody was raised against a peptide from N terminal residues of human APAF1 protein. |
| Other Names | [APAF1 protein; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1], [APAF1; APAF1; CED4; APAF-1] |
| Gene, Accession # | [Apaf1], Gene ID: 317, NCBI: ABQ59028.1 |
| Catalog # | MBS415532 |
| Price | $230 |
| Order / More Info | Apaf1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | (1) Manns,J., Daubrawa,M., Driessen,S. Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1. FASEB J. 25 (9), 3250-3261 (2011). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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