RNA Polymerase II CTD Repeat YSPTSPS (Phospho S5) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRNA Polymerase II CTD Repeat YSPTSPS (Phospho S5)
Clone[CTD 8A7]
Host SpeciesMouse
Reactive Specieshuman, Saccharomyces cerevisiae
IsotypeIgM, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: RNA polymerase II (Pol II) is an enzyme that is composed of 12 subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large sub
ImmunogenImmunogen: Ten repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-Ser5
Other Names[DNA-directed RNA polymerase II largest subunit RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit RPB1; hRPB220; hsRPB1; POLR2; Polr2a; POLRA; Polymerase (RNA) II (DNA directed) polypeptide A 220kDa; RNA polymerase II subunit B1; RPBh1; RpIILS; RPO2; RPOL2]
Gene, Accession #[POLR2A], Gene ID: 5430, NCBI: NP_000928.1, UniProt: P24928
Catalog #MBS4381181
Price$190, $340, $340
Order / More InfoRNA Polymerase II CTD Repeat YSPTSPS (Phospho S5) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMadak-Erdogan, Z., et al. 2008. Mol. Endocrinol. 22: 2116-2127
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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