KPNA1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKPNA1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionKaryopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the amino terminus of human KPNA1.
Other Names[Karyopherin alpha 1 Nucleoprotein interactor 1, Importin alpha 5, IPOA5, RAG cohort protein 2, RCH2, SRP1, NPI-1]
Gene, Accession #[KPNA1], Gene ID: 3836, NCBI: NP_002255
Catalog #MBS9401772
Price$320
Order / More InfoKPNA1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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