Human CD106/VCAM-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD106/VCAM-1 |
| Clone | [1.G11B1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA; Flow Cytometry; Immunohistochemistry (Frozen Sections); Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human CD106/VCAM-1. CD106, also known as INCAM-1, is a 100-110 kDa vascular adhesion cell adhesion molecule-1 (VCAM- 1) that is member of the immunoglobulin superfamily. CD106 is expressed predominantly on cytokineactivated vascular endothelium but has also been identified on interfollicular dendritic cells, some macrophages and bone marrow stromal cells. Endothelial CD106 binds the integrins alpha 4 beta 1 (CD49d/CD29, VLA-4) and alpha 4 beta 7 and contributes to extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, particularly at sites of inflammation. Unlike the beta 2 integrins, the CD106-VLA-4 interaction can mediate both the initial tethering and rolling of lymphocyt |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS674158 |
| Price | $165 |
| Order / More Info | Human CD106/VCAM-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford.2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD106 Section, Academic Press, New York, p. 386.3. Thornhill, M.H., S.M. Wellicome, D.L. Mahiouz, J.S. Lanchbury, U. Kyan-Aung, and D.O. Haskard. 1991. J. Immunol. 146:592.4. Bevilacqua, M.P. 1993. Annu. Rev. Immunol. 11:767. |
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MYBIOSOURCE INC.
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