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Antigenic Specificity | MMP14/Mt1 Mmp |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro- MMP2. |
Immunogen | Immunogen: A synthesized peptide derived from human MMP14. Subcellular Localization: Membrane; Single-pass type I membrane protein. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm. Tissue Specificity: Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors. |
Other Names | [Matrix metalloproteinase-14; MMP-14; 3.4.24.80; MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMP; MMP14], [MMP14; MMP14; MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1; MMP-14; MT-MMP 1; MTMMP1; MT1-MMP; MT1MMP] |
Gene, Accession # | [MMP14], Gene ID: 4323, NCBI: NP_004986.1, UniProt: P50281 |
Catalog # | MBS179406 |
Price | $160, $340, $340 |
Order / More Info | MMP14/Mt1 Mmp Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |