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Antigenic Specificity | Nop30, |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD)bcontaining molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf 1, caspase 9 and caspase 2. Apoptosis repressor with CARD is a CARD domain containing protein that interacts with caspase 2 and 8 to inhibit enzymatic activity of caspase 8. Apoptosis repressor with CARD suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR 1, and DR3. The mRNA of Apoptosis repressor with CARD is primarily expressed in skeletal muscle and cardiac tissue. The nuclear isoform (1/Nop30) may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apo |
Immunogen | Immunogen: CPELQTLTRPGALRAPRRC |
Other Names | [nucleolar protein 3 isoform Nop30; Nucleolar protein 3; nucleolar protein 3; nucleolar protein 3; Apoptosis repressor with CARD], [NOL3; NOL3; ARC; FCM; MYP; NOP; NOP30; Nop30] |
Gene, Accession # | [Nop30], Gene ID: 8996, NCBI: NP_001171986.1 |
Catalog # | MBS555315 |
Price | $260 |
Order / More Info | Nop30, Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |