14-3-3-eta Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | 14-3-3-eta |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 100ug/100ul |
| Applications | Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human, mouse and rat. 14-3-3-eta is a Protein 14-3-3 is a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases (191290, 191060) and an endogenous inhibitor of protein kinase C (176960). The 14-3-3 protein exists in several distinct forms: e.g., beta (YWHAB; 601289), gamma (YWHAG; 605356), epsilon (YWHAE; 605066), zeta (YWHAZ; 601288), theta (YWHAQ; 609009), sigma (SFN; 601290), and eta (YWHAH). |
| Immunogen | Immunogen: The 14.3.3 family of proteins were originally discovered as prominent protein spots on 2 dimensional gels. They are a family of 28-33kDa proteins which are often major proteins of the cytoplasm (1). They function as binding partners for phosphoserine and phosphthreonine sites in other proteins, though they have other binding partners which are not dependent on phosphorylation. These binding interactions are important in the regulation of molecules such as the signaling kinases in the |
| Other Names | [14-3-3-eta], [YWHAH; YWHAH; YWHA1; YWHA1] |
| Gene, Accession # | [14-3-3-eta], Gene ID: 7533, NCBI: NP_003396.1, UniProt: Q04917 |
| Catalog # | MBS415252 |
| Price | $370 |
| Order / More Info | 14-3-3-eta Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Morrison, DK. The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development. Trends Cell Biol. 19:16-23 (2009).2. Hsich G, Kenney K, Gibbs CJ, Lee KH and Harrington MG. The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies. N Engl J Med. 335:924-30 (1996).3: Ubl A, Berg D, Holzmann C, Kr ger R, Berger K, Arzberger T, Bornemann A, Riess O. 14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta. Brain Res Mol Brain Res. 108(1-2):33-9 (2002).4: Middleton FA, Peng L, Lewis DA, Levitt P, Mirnics K. Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia. Neuropsychopharmacology 30(5):974-83 (2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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