Human CD91 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD91
Clone[A2Mr alpha-2]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatno preservative
Size1 mg
ConcentrationIgG concentration 1.0mg/ml
ApplicationsImmunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB)*
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DescriptionMouse anti Human CD91 antibody, clone A2Mr alpha-2 recognizes human CD91, also known as Prolow-density lipoprotein receptor-related protein 1, Alpha-2-macroglobulin receptor or apolipoprotein E receptor. CD91 is a 4525 amino acid protein post translationally cleaved into 3 subunits, a 85kDa type I transmembrane carboxyl chain (LRP85) non-covalently bound to a 515kDa extracellular N-terminal subunit (LRP515)containing multiple EGF-like and LDL-receptor Class A and Class B domains. Additionally, there is an intracellular domain (LRPICD) which can be cleaved from the transmambrane domain by gamma secretase (May et al. 2004). Clone A2Mr alpha-2 detects an epitope within the LRP515 chain. CD91 is a multifunctional protein involved in processes i
Immunogenn/a
Other Names[prolow-density lipoprotein receptor-related protein 1; Prolow-density lipoprotein receptor-related protein 1; prolow-density lipoprotein receptor-related protein 1; LRP-1; TbetaR-V/LRP-1/IGFBP-3 receptor; alpha-2-macroglobulin receptor; apolipoprotein E receptor; type V tgf-beta receptor; low density lipoprotein receptor-related protein 1; Alpha-2-macroglobulin receptor; A2MR; Apolipoprotein E receptor; APOER; CD_antigen: CD91Cleaved into the following 3 chains:Low-density lipoprotein receptor-related protein 1 85 kDa subunit; LRP-85; Low-density lipoprotein receptor-related protein 1 515 kDa subunit; LRP-515; Low-density lipoprotein receptor-related protein 1 intracellular domain; LRPICD], [LRP1; LRP1; APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R; A2MR; APR; LRP-1; A2MR; APOER; LRP-85; LRP-515; LRPICD]
Gene, Accession #[CD91], Gene ID: 4035, NCBI: NP_002323.2, UniProt: Q07954
Catalog #MBS210197
Price$750
Order / More InfoHuman CD91 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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