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Antigenic Specificity | MYH9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nonmuscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity. The holoenzyme consists of two identical heavy chains and two sets of light chains. The light chains (MLCs) regulate myosin II activity and stability. The heavy chains (NMHCs) are encoded by three genes, MYH9, MYH10, and MYH14, which generate three different nonmuscle myosin II isoforms, IIa, IIb, and IIc, respectively (reviewed in 1). While all three isoforms perform the same enzymatic tasks, binding to and contracting actin filaments coupled to ATP hydrolysis, their cellular functions do not appear to be redundant and they have different subcellular distributions (2-5). The carboxy-terminal tail domain of myosin I |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Myosin IIa: MYH9; DFNA17; EPSTS; FTNS; MGC104539; MHA; NMHC-II-A; NMMHCA; Myosin Iia], [MYH9; MYH9; MHA; FTNS; EPSTS; BDPLT6; DFNA17; NMMHCA; NMHC-II-A; NMMHC-IIA; NMMHC-A; NMMHC II-a; NMMHC-IIA] |
Gene, Accession # | [MYH9], Gene ID: 4627, NCBI: P35579.4, UniProt: P35579 |
Catalog # | MBS125840 |
Price | $200, $275, $430 |
Order / More Info | MYH9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |