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Antigenic Specificity | Cyclin E2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cyclin E2 Antibody detects endogenous levels of total Cyclin E2. The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. |
Immunogen | Immunogen: A synthesized peptide derived from human Cyclin E2 |
Other Names | [CGE2; cyclin E2; G1/S-Specific cyclin E2] |
Gene, Accession # | [CYCE2], Gene ID: 9134, NCBI: NP_477097.1, UniProt: O96020 |
Catalog # | MBS4750058 |
Price | $335 |
Order / More Info | Cyclin E2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |