SLC22A17 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | SLC22A17 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mL |
| Concentration | 1.2 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total SLC22A17 protein. Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis. |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human solute carrier family 22, member 17 |
| Other Names | [BOCT; BOIT; 24p3R; NGALR; hBOIT; NGALR2; NGALR3] |
| Gene, Accession # | [SLC22A17], Gene ID: 51310, NCBI: NP_001275979.1, UniProt: Q8WUG5 |
| Catalog # | MBS9411964 |
| Price | $255 |
| Order / More Info | SLC22A17 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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