CAPRIN1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCAPRIN1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: CAPRIN1 antibody detects endogenous levels of CAPRIN1. Function: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.Subunit Structure: May form homomultimers (By similarity). Interacts with G3BP1; interaction is direct and takes place in cytoplasmic RNA granules (PubMed:17210633). Interacts with PQBP1 (PubMed:21933836).Post-translational Modifications: O-glycosylated (O-
ImmunogenImmunogen: A synthesized peptide derived from human CAPRIN1. Subcellular Location: Cytoplasm > Cytosol. Cell Projection > Dendrite. Associated with RNA granules. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (88%), Sheep (100%), Dog (100%), Chicken (88%)
Other Names[activation/proliferation-associated protein 1; CAPR1_HUMAN; Caprin-1; CAPRIN1; Cell cycle-associated protein 1; Cytoplasmic activation-and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; GPIAP1; M11S1; Membrane component chromosome 11 surface marker 1; p137GPI; RNA granule protein 105; RNG105]
Gene, Accession #[CAPRIN1], Gene ID: 4076, NCBI: NP_005889.3, UniProt: Q14444
Catalog #MBS9603240
Price$240, $280
Order / More InfoCAPRIN1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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