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Antigenic Specificity | DKK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Xenopus Dickkopf (Dkk) 1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine rich domains. Recent studies showed that the second Cys rich domains of Dkk1 and Dkk2 inhibited Wnt 3a activated signaling, whereas the first Cys rich domains had no effects. In addition, the second Cys rich domain of Dkk 2, but not that of Dkk 1, was able to activate the canonical pathway in the presence of LRP6, and this LRP dependent signaling does not require Dvl. |
Immunogen | Immunogen: DKK1 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 255 of mouse Dkk1 as the immunogen. |
Other Names | [Rabbit DKK1; DKK1; DKK1; DKK-1; Dickkopf related protein 1; DKK1; DKK 1; DKK-1; DKK 1; DKK-1] |
Gene, Accession # | [DKK1] |
Catalog # | MBS5309167 |
Price | $705 |
Order / More Info | DKK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |